GENERAL MEDICINE CASE DISCUSSION

Surigi Mounika 160
Date : 16/05/2020  

WOMEN WITH MULTIPLE HEALTH PROBLEMS SINCE BIRTH 
I have been given this case to solve in an attempt to understand the topic of "patient clinical data analysis"to develope my competency in reading and comprehending clinical data including history taking, clinical findings, investigations ,diagnosis and treatment. 

You can find entire real patient clinical problem in this linkhttps://classworkdecjan.blogspot.com/2019/05/42-f-with-severe-regular-edema-with_17.html?m=

Following is my analysis of this patient's problem:

The problem in order of priority I found are 
1 SEVERE HEAD ACHE 
2.swelling 
3.muscle weakness 
4.sensory processing disorder 
5.Mouth ulcers 
6.Excessive hair growth 
                
            SEVERE HEADACHE 
Onset:sudden 
Duration:2years
Associated with aura before headache: rainbow colours,blindness 
Left side hand numbness 
Ataxia( Leftside)
Vertigo
Stuttering of speech and sleep disturbance.
Aggravating with:
1.stress 
2.menses 
3.OC pills.
4.one episode of nasal discharge for about 10 mins on bending forward 
 DIAGNOSIS:
HEMIPLEGIA MIGRAIN. 
Factors responsible for this condition are
.Stress 
.less sleep 
.Excess exercise 
.Avoiding meals
.oc pills
.travel history 
. Smoke
INVESTIGATIONS:
Funds examination 
CT and MRI 
DOPPLER 
Xray paranasal sinuses
                                  
 TREATMENT:                                
Triptans.
ERENUMAB(CGRP INHIBITOR)
         
                SWELLING 
Onset:at age 1 year 
Duration: still present 
Aggravating factors:
         Emotional stress 
          Smoke 
         Eating wrong food 
          Physical activity 
          Antimalarials 
           Fava beans
           Sulfa drugs 

Mainly in face , neck and abdomen. 
DIAGNOSIS: 
It may be associated with G6PD deficiency ( Hemolytic crisis)
FACTORS TRIGGERS IN THIS PATIENT:
            Infection: recurrent UTI and 
                                Pneumonia. 
             Antimalarials 
             Sulfa drugs
              Fava beans 
Symptoms associated with this condition in this patient: 
Coke colour urine
Diarrhoea 
Vomiting 
Swelling 
Acute kidney failure. 

EXAMINATION:
.Any episode of jundice
.hemolysis conditions. 
INVESTIGATIONS:
CBP
Liver enzymes
Reticulocyte counts 
Bilirubin levels 
 Haptoglobin level 
Coombs test (negative in this case)
BEUTLER FLORESCENT SPOT TEST
Peripheral smear: bite cells , Blister cells ,HEINZ bodies. 

TREATMENT: 
Avoid oxidative stress 
Vaccination against pneumonia 
Blood transfusion
Apple ( anti oxidant property).

MUSCLE WEAKNESS:
AMPD1 deficiency
                   |
Excess adenosine 
                    |
Decreased altertness and fatigue
                      Muscle weakness 
Treatment:
Ribose.

 SENSORY PROCESSING DISORDER:Numbness in left side of face and loss of function of left side. 
Associated with migrane attack
DIAGNOSIS: Hemiplegic migraine.

OTHER PROBLEMS: 
Mouth ulcers 
Vaginal ulcers 
Blurring of vision 
Long term knee and hip pain
Differential diagnosis:
SLE
Behcets disease 
INVESTIGATIONS
 Antibodies testing forSLE
BLOOD tests 
Genetic testing 
Allergy testing 
Pathergy test
Treatment:
1.Corticosteroids 
2.Colchicine 
3.Immunosuppressants

EXCESSIVE HAIR GROWTH :
On face, neck, toes,legs in 4 years
D/D
1.PCOS 
2.congenital adrenal hyperplasia 
INVESTIGATIONS 
1.CT scan for PCOS 
2.cortisol levels
TREATMENT:
Spironolactone 
Anti androgens
Eflornithine
Eletrolysis

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